Non steroid drugs for asthma

Benefits of NSAIDs still outweigh the risks and most users are benefiting greatly from the use of these over the counter pain killers for their painful joints or headaches. In fact NSAIDs are considered indispensible for pain management. The choice of NSAID is usually based on personal experience rather than evidence. According to the American College of Gastroenterology estimates that 14 million arthritis patients use NSAIDS continuously. 80% NSAID users complained of gastrointestinal side effects like stomach pain and ulcers. However, adding a proton pump inhibitor can help with these problems. Those most at risk for NSAID induced ulcers are the elderly, smokers, alcoholics, people who use multiple NSAIDs. The efficiency of the use of multiple NSAIDs has not been established as well. The patient’s ability to heal from ulcers or internal bleeding depends on age and other relevant factors. 1-2% people on NSAIDs do develop a frightening ulcer complication however. According to the American College of Gastroenterology, around 10 percent continuous NSAIDS users quit their medication because of troublesome gastrointestinal side effects.

A variety of allergic or allergic-like NSAID hypersensitivity reactions follow the ingestion of NSAIDs. These hypersensitivity reactions differ from the other adverse reactions listed here which are toxicity reactions, . unwanted reactions that result from the pharmacological action of a drug, are dose-related, and can occur in any treated individual; hypersensitivity reactions are idiosyncratic reactions to a drug. [67] Some NSAID hypersensitivity reactions are truly allergic in origin: 1) repetitive IgE -mediated urticarial skin eruptions, angioedema , and anaphylaxis following immediately to hours after ingesting one structural type of NSAID but not after ingesting structurally unrelated NSAIDs; and 2) Comparatively mild to moderately severe T cell -mediated delayed onset (usually more than 24 hour), skin reactions such as maculopapular rash , fixed drug eruptions , photosensitivity reactions , delayed urticaria , and contact dermatitis ; or 3) far more severe and potentially life-threatening t-cell-mediated delayed systemic reactions such as the DRESS syndrome , acute generalized exanthematous pustulosis , the Stevens–Johnson syndrome , and toxic epidermal necrolysis . Other NSAID hypersensitivity reactions are allergy-like symptoms but do not involve true allergic mechanisms; rather, they appear due to the ability of NSAIDs to alter the metabolism of arachidonic acid in favor of forming metabolites that promote allergic symptoms. Afflicted individuals may be abnormally sensitive to these provocative metabolites or overproduce them and typically are susceptible to a wide range of structurally dissimilar NSAIDs, particularly those that inhibit COX1. Symptoms, which develop immediately to hours after ingesting any of various NSAIDs that inhibit COX-1, are: 1) exacerbations of asthmatic and rhinitis (see aspirin-induced asthma ) symptoms in individuals with a history of asthma or rhinitis and 2) exacerbation or first-time development of wheals or angioedema in individuals with or without a history of chronic urticarial lesions or angioedema. [26]

Olive fruit oil – nourishing, anti-bacterial.
Beeswax – a natural emulsifier, provides a protective base and keeps the skin moisturised.
Safflower seed oil – excellent for sensitive skin.
Hemp seed oil – extremely nourishing, moisturising, rich in essential fatty acids (EFA’s), which are often lacking in those dry skin.
Tincture of nettle – rich in vitamins chickweed – rich in vitamin c, iron, calcium, potassium.
Tincture of calendula – for tissue regeneration.
Camomile – for softening and soothing.”

Non steroid drugs for asthma

non steroid drugs for asthma

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