Non-steroidal aromatase inhibitors breast cancer

In rodents, estrogens (which are locally aromatized from androgens in the brain) play an important role in psychosexual differentiation, for example, by masculinizing territorial behavior; [56] the same is not true in humans. [57] In humans, the masculinizing effects of prenatal androgens on behavior (and other tissues, with the possible exception of effects on bone) appear to act exclusively through the androgen receptor. [58] Consequently, the utility of rodent models for studying human psychosexual differentiation has been questioned. [59]

Non-steroidal aromatase inhibitors breast cancer

non-steroidal aromatase inhibitors breast cancer

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